Dynamics of maternal morphogen gradients in Drosophila
نویسندگان
چکیده
منابع مشابه
Dynamics of maternal morphogen gradients in Drosophila.
The first direct studies of morphogen gradients were done in the end of 1980s, in the early Drosophila embryo, which is patterned under the action of four maternally determined morphogens. Since the early studies of maternal morphogens were done with fixed embryos, they were viewed as relatively static signals. Several recent studies analyze dynamics of the anterior, dorsoventral, and terminal ...
متن کاملSelf-similar dynamics of morphogen gradients.
Morphogen gradients are concentration fields of molecules acting as spatial regulators of cell differentiation in developing tissues and play a fundamental role in various aspects of embryonic development. We discovered a family of self-similar solutions in a canonical class of nonlinear reaction-diffusion models describing the formation of morphogen gradients. These solutions are realized in t...
متن کاملScaling of morphogen gradients.
Individuals of the same or closely related species can vary substantially in size. Still, the proportions within and between tissues are precisely kept. This adaptation of pattern with size termed scaling, is receiving a growing attention. We review experimental evidence for scaling, and describe theoretical models for mechanisms that scale morphogen gradients. We particularly note the Expansio...
متن کاملDynamics and precision in retinoic acid morphogen gradients.
Retinoic acid (RA) regulates many cellular behaviors during embryonic development and adult homeostasis. Like other morphogens, RA forms gradients through the use of localized sources and sinks, feedback, and interactions with other signals; this has been particularly well studied in the context of hindbrain segmentation in vertebrate embryos. Yet, as a small lipophilic molecule derived from a ...
متن کاملShaping Morphogen Gradients
Shh activity and at different distances from the source. The proper functioning of tissues and organs requires These observations provide unequivocal evidence that that each cell differentiate appropriately for its position. Shh acts directly on distant cells and therefore that Shh In many cases, the positional information that instructs forms a morphogen gradient in the developing neural cells...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Opinion in Genetics & Development
سال: 2008
ISSN: 0959-437X
DOI: 10.1016/j.gde.2008.06.002